Effizientes binaurales Rendering von virtuellen akustischen Realitäten : technische und wahrnehmungsbezogene Konzepte

Binaural rendering aims to immerse the listener in a virtual acoustic scene, making it an essential method for spatial audio reproduction in virtual or augmented reality (VR/AR) applications. The growing interest and research in VR/AR solutions yielded many different methods for the binaural rendering of virtual acoustic realities, yet all of them share the fundamental idea that the auditory experience of any sound field can be reproduced by reconstructing its sound pressure at the listener's eardrums. This thesis addresses various state-of-the-art methods for 3 or 6 degrees of freedom (DoF) binaural rendering, technical approaches applied in the context of headphone-based virtual acoustic realities, and recent technical and psychoacoustic research questions in the field of binaural technology. The publications collected in this dissertation focus on technical or perceptual concepts and methods for efficient binaural rendering, which has become increasingly important in research and development due to the rising popularity of mobile consumer VR/AR devices and applications. The thesis is organized into five research topics: Head-Related Transfer Function Processing and Interpolation, Parametric Spatial Audio, Auditory Distance Perception of Nearby Sound Sources, Binaural Rendering of Spherical Microphone Array Data, and Voice Directivity. The results of the studies included in this dissertation extend the current state of research in the respective research topic, answer specific psychoacoustic research questions and thereby yield a better understanding of basic spatial hearing processes, and provide concepts, methods, and design parameters for the future implementation of technically and perceptually efficient binaural rendering.Binaurales Rendering zielt darauf ab, dass der Hörer in eine virtuelle akustische Szene eintaucht, und ist somit eine wesentliche Methode für die räumliche Audiowiedergabe in Anwendungen der virtuellen Realität (VR) oder der erweiterten Realität (AR – aus dem Englischen Augmented Reality). Das wachsende Interesse und die zunehmende Forschung an VR/AR-Lösungen führte zu vielen verschiedenen Methoden für das binaurale Rendering virtueller akustischer Realitäten, die jedoch alle die grundlegende Idee teilen, dass das Hörerlebnis eines beliebigen Schallfeldes durch die Rekonstruktion seines Schalldrucks am Trommelfell des Hörers reproduziert werden kann. Diese Arbeit befasst sich mit verschiedenen modernsten Methoden zur binauralen Wiedergabe mit 3 oder 6 Freiheitsgraden (DoF – aus dem Englischen Degree of Freedom), mit technischen Ansätzen, die im Kontext kopfhörerbasierter virtueller akustischer Realitäten angewandt werden, und mit aktuellen technischen und psychoakustischen Forschungsfragen auf dem Gebiet der Binauraltechnik. Die in dieser Dissertation gesammelten Publikationen befassen sich mit technischen oder wahrnehmungsbezogenen Konzepten und Methoden für effizientes binaurales Rendering, was in der Forschung und Entwicklung aufgrund der zunehmenden Beliebtheit von mobilen Verbraucher-VR/AR-Geräten und -Anwendungen zunehmend an Relevanz gewonnen hat. Die Arbeit ist in fünf Forschungsthemen gegliedert: Verarbeitung und Interpolation von Außenohrübertragungsfunktionen, parametrisches räumliches Audio, auditive Entfernungswahrnehmung ohrnaher Schallquellen, binaurales Rendering von sphärischen Mikrofonarraydaten und Richtcharakteristik der Stimme. Die Ergebnisse der in dieser Dissertation enthaltenen Studien erweitern den aktuellen Forschungsstand im jeweiligen Forschungsfeld, beantworten spezifische psychoakustische Forschungsfragen und führen damit zu einem besseren Verständnis grundlegender räumlicher Hörprozesse, und liefern Konzepte, Methoden und Gestaltungsparameter für die zukünftige Umsetzung eines technisch und wahrnehmungsbezogen effizienten binauralen Renderings.BMBF, 03FH014IX5, Natürliche raumbezogene Darbietung selbsterzeugter Schallereignisse in virtuellen auditiven Umgebungen (NarDasS

How positioning inaccuracies influence the spatial upsampling of sparse head-related transfer function sets

Determining full-spherical individual sets of head-related transfer functions (HRTFs) based on sparse measurements is a prerequisite for various applications in virtual acoustics. To obtain dense sets from sparse measurements, spatial upsampling of sparse HRTF sets in the spatially continuous spherical harmonics (SH) domain can be performed by an inverse SH transform. However, this involves artifacts caused by spatial aliasing and order truncation. In a previous publication we presented the SUpDEq method (Spatial Upsampling by Directional Equalization), which reduces these artifacts by a directional equalization prior to the SH transform. Generally, apart from the spatial resolution of the HRTF set, measurement inaccuracies, for example caused by displacements of the head during the measurement, can influence the spatial upsampling as well. By this direction-depending temporal and spectral deviations are added to the dataset, which in the process of spatial upsampling can cause artifacts comparable to spatial aliasing errors. To reduce the influence of the distance inaccuracies, we present a method for distance error compensation that performs an appropriate distance-shifting of the measured HRTFs. Determining the required values for the shift benefits from the directional equalization performed by SUpDEq and results in time-aligning the directionally equalized HRTFs. We analyze the influence of the angular and distance displacements on spectrum, on interaural cues and on modeled localization performance. While limited angular inaccuracies only have a low impact, already small random distance displacements cause strong impairments, which can be significantly reduced applying the proposed distance error compensation method

High-resolution serum proteome trajectories in COVID-19 reveal patient-specific seroconversion

Abstract A deeper understanding of COVID‐19 on human molecular pathophysiology is urgently needed as a foundation for the discovery of new biomarkers and therapeutic targets. Here we applied mass spectrometry (MS)‐based proteomics to measure serum proteomes of COVID‐19 patients and symptomatic, but PCR‐negative controls, in a time‐resolved manner. In 262 controls and 458 longitudinal samples of 31 patients, hospitalized for COVID‐19, a remarkable 26% of proteins changed significantly. Bioinformatics analyses revealed co‐regulated groups and shared biological functions. Proteins of the innate immune system such as CRP, SAA1, CD14, LBP, and LGALS3BP decreased early in the time course. Regulators of coagulation (APOH, FN1, HRG, KNG1, PLG) and lipid homeostasis (APOA1, APOC1, APOC2, APOC3, PON1) increased over the course of the disease. A global correlation map provides a system‐wide functional association between proteins, biological processes, and clinical chemistry parameters. Importantly, five SARS‐CoV‐2 immunoassays against antibodies revealed excellent correlations with an extensive range of immunoglobulin regions, which were quantified by MS‐based proteomics. The high‐resolution profile of all immunoglobulin regions showed individual‐specific differences and commonalities of potential pathophysiological relevance

Where Brain, Body and World Collide

The production cross section of electrons from semileptonic decays of beauty hadrons was measured at mid-rapidity (|y| < 0.8) in the transverse momentum range 1 < pt < 8 Gev/c with the ALICE experiment at the CERN LHC in pp collisions at a center of mass energy sqrt{s} = 7 TeV using an integrated luminosity of 2.2 nb^{-1}. Electrons from beauty hadron decays were selected based on the displacement of the decay vertex from the collision vertex. A perturbative QCD calculation agrees with the measurement within uncertainties. The data were extrapolated to the full phase space to determine the total cross section for the production of beauty quark-antiquark pairs

Energy Dependence of the Transverse Momentum Distributions of Charged Particles in pp Collisions Measured by ALICE

Differential cross sections of charged particles in inelastic pp collisions as a function of p_T have been measured at $\sqrt{s}$ = 0.9, 2.76 and 7 TeV at the LHC. The $p_T$ spectra are compared to NLO-pQCD calculations. Though the differential cross section for an individual $\sqrt{s}$ cannot be described by NLO-pQCD, the relative increase of cross section with sqrt(s) is in agreement with NLO-pQCD. Based on these measurements and observations, procedures are discussed to construct pp reference spectra at $\sqrt{s}$ = 2.76 and 5.02 TeV up to $p_T$ = 50 GeV/c as required for the calculation of the nuclear modification factor in nucleus-nucleus and proton-nucleus collisions